Mental Vaccine: How to Strengthen Your Resistance Against Fake News
- Lidi Garcia
- Mar 17
- 5 min read

The study showed that educational interventions can help people resist misinformation, but their effects diminish over time. Videos and texts remain effective for about a month, while games lose their impact more quickly. The main reason for this loss is lack of memory for the content, not lack of motivation. Reinforcing learning may be key to making these interventions more lasting.
Misinformation poses a significant threat to society and the functioning of democracies around the world. This is because the spread of false information can influence public opinion and political decisions, often without people realizing they are being manipulated.
Studies have shown that misinformation has impacted critical areas such as vaccine acceptance, support for policies to combat global warming, and even the outcomes of political elections.
Furthermore, in more serious cases, the spread of false information has been linked to episodes of real violence, such as mob attacks in India and the destruction of 5G transmission towers by people believing in misguided conspiracy theories.

Many efforts to combat misinformation currently rely on so-called “debunking,” or correcting false information after it has already spread.
While this approach can have positive effects, research suggests that it is more effective to adopt a preventative strategy, preventing people from believing and sharing misinformation before they are even exposed to it.
One such preventative strategy is called “psychological inoculation,” a concept inspired by medical vaccination.
Just as a vaccine teaches the immune system to recognize and fight off a virus, psychological inoculation prepares people to identify and resist misinformation.
This is done through interventions that alert the public to the techniques used to deceive and deliver small, controlled doses of misinformation, allowing people to learn to recognize patterns of manipulation and develop resistance against them.
In recent years, scientists have tested different ways of applying this strategy. Some interventions use educational texts to teach people how to identify fake news, others use short videos that illustrate common manipulation tactics and, more recently, interactive games have even emerged in which participants take on the role of creators of disinformation to learn, in a safe and controlled way, how these strategies work.

The goal of these approaches is to make the public more critical and less vulnerable to fake news. While some of these interventions focus on specific topics, such as climate change or anti-vaccine campaigns, others seek to teach general skills for detecting misinformation, such as identifying the overuse of emotional appeals, the manipulation of data, or the spread of logical fallacies.
To better understand the effectiveness of these interventions, researchers have investigated different factors that may influence their durability. Classical inoculation theory proposes that it works because it increases threat perception, that is, it makes people feel like they can be deceived, and it also makes individuals more familiar with the tricks used to manipulate public opinion.
This motivates them to protect themselves against misinformation and improves their ability to resist misleading arguments.
However, some experts argue that memory may be an even more important factor than motivation: the better a person remembers the information taught in the intervention, the greater their resilience to misinformation in the future. Others argue that both factors, memory and motivation, work together to prolong the effects of inoculation.
Despite advances in the study of psychological inoculation, three major unanswered questions remain: (1) how long do the effects of these interventions last, (2) why do they diminish over time, and (3) how can we make them last longer?

Currently, there is not enough research that has systematically examined these factors, and this limits the potential of these strategies in real life. To address this issue, this study investigates the durability of psychological inoculation and looks for ways to strengthen its effects over time.
The researchers conducted experiments to evaluate three types of inoculation interventions:
Educational text (Study 1): A group of participants received an informative text that explained how misinformation about global warming is spread and how to recognize false arguments about the topic. This approach was designed to be passive, meaning that people simply consumed the information without having to interact with it.
Interactive game (Study 2): In this experiment, participants played a game called “Bad News,” where they had to create and spread fictional fake news in a controlled manner. The idea was that by experiencing how misinformation works in practice, players would become more critical and resistant to it in real life. The game featured humorous and exaggerated examples to ensure that participants did not absorb the misinformation in a negative way.
Educational video (Studies 3–5): Another group watched short videos teaching how to identify a common manipulation technique: the use of emotional language to deceive people. These videos had been tested before and had been viewed by millions of users on YouTube. However, it was not yet known how long their effects lasted after viewing.
To measure the effectiveness of these interventions, the researchers assessed the participants at three different time points: immediately after the intervention (T0), about 10 days later (T10), and about a month later (T30). In addition, some of the volunteers received a “booster” of the intervention at T10, to test whether reapplying the content helped maintain its effects.

The results showed that text- and video-based interventions maintained their effectiveness for at least a month, while game-based interventions had a shorter effect.
Furthermore, the main reason for the loss of effectiveness over time was found to be decreased memory for the content, rather than lack of motivation. This suggests that reinforcing recall of learned material may be an effective way to prolong the benefits of interventions.
Based on these findings, the researchers propose a new theoretical model called the “memory-motivation model,” which combines insights from the psychology of memory with the principles of psychological inoculation.
This model argues that while motivation helps to strengthen learning, memory is the primary factor that determines how long resistance to misinformation will last.
In summary, the study provides new evidence that psychological inoculation is a powerful tool for combating misinformation and highlights the importance of developing strategies that reinforce audience memory to increase the durability of these interventions.
The findings suggest that researchers and policymakers can create more effective and lasting campaigns by incorporating principles of cognitive science into the fight against misinformation.
READ MORE:
Psychological booster shots targeting memory increase long-term resistance against misinformation
Rakoen Maertens, Jon Roozenbeek, Jon S. Simons, Stephan Lewandowsky, Vanessa Maturo, Beth Goldberg, Rachel Xu & Sander van der Linden
Nature Communications, volume 16, Article number: 2062 (2025)
Abstract:
An increasing number of real-world interventions aim to preemptively protect or inoculate people against misinformation. Inoculation research has demonstrated positive effects on misinformation resilience when measured immediately after treatment via messages, games, or videos. However, very little is currently known about their long-term effectiveness and the mechanisms by which such treatment effects decay over time. We start by proposing three possible models on the mechanisms driving resistance to misinformation. We then report five pre-registered longitudinal experiments (Ntotal = 11,759) that investigate the effectiveness of psychological inoculation interventions over time as well as their underlying mechanisms. We find that text-based and video-based inoculation interventions can remain effective for one month—whereas game-based interventions appear to decay more rapidly—and that memory-enhancing booster interventions can enhance the diminishing effects of counter-misinformation interventions. Finally, we propose an integrated memory-motivation model, concluding that misinformation researchers would benefit from integrating knowledge from the cognitive science of memory to design better psychological interventions that can counter misinformation durably over time and at-scale.
Yorumlar